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Many people describe early changes within one to two weeks for acute soft-tissue issues, gut-related use is sometimes felt sooner, and chronic injuries can take four to eight weeks or longer

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In case of fatty acid oxidation defects, acyl-carnitines accumulate in mitochondria and are transferred into the cytosol, and then into the blood

Bottom Line Ozempic pen injections should stay refrigerated (between 36F to 46F or 2C to 8C) until the first time you use it

Mild side effects can include nausea, flushing, dizziness, and localized irritation at the injection site

Kulich et al., 2008)