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The alignment highlights that class III GRXs do not encode the class II-specific five amino acid loop which interferes with oxidoreductase activity 14,15 , nor the proline in the active site which might interfere with FeS cluster assembly 16

Interaction of quercetin and 5-fluorouracil: cellular and pharmacokinetic study

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De Candia et al., 2021)

Epithalons ability to activate telomerase and elongate telomeres has been shown in research to extend the number of cell divisions beyond the normal Hayflick Limit, effectively extending the replicative lifespan of treated cells.