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Cell viability for GHK-Cu was previously investigated by Hairui et al, showing no significance difference between the control and the GHK-Cu treated group at the same concentrations and time points, implying the non-cytotoxic nature of GHK-Cu towards HaCaT 11

Conen D, Glynn RJ, Buring JE, Ridker PM, Zee RY

Moreover, berberine and pioglitazone have similar binding affinity to peroxisome proliferator-activated receptor gamma (PPAR) protein, have an overlapping effect on Alzheimers disease (Wong et al., 2021)

Cobalamin deficiency