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Warning signs include sudden leg swelling with pain and warmth, sudden shortness of breath or chest pain, coughing up blood, or stroke symptoms like facial drooping and speech difficulty

Hypericin - the facts about a controversial agent

In the fourth and last stage of B12 deficiency, clinical manifestations are experienced by the individual including macrocytic anemia (a form of anemia in which red blood cells are larger than usual, hence the term macro) and, if left untreated, irreversible neurological damage

The relative fluorescence intensities were measured at the excitation wavelength ( Ex ) of 560 nm and emission wavelength ( Em ) of 590 nm