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On May 12, 2023, LaNova Medicines announced the signing of an exclusive licensing agreement with AstraZeneca for LM-305, a pre-clinical stage antibody-drug conjugate comprising an anti-GPRC5D monoclonal antibody, a degradable protease linker, and a cytotoxic payload of MMAE

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Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells