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Organ Growth Concerns at High Doses Because IGF-1 acts on all tissue not just muscle megadosing for extended periods may promote organ tissue hypertrophy, including intestinal walls and heart tissue
PubMed Kang YA et al
Liu L, Yan H, Xia M, Zhao L, Lv M, Zhao N, et al
IGF-1 DES Structure Sequence: TLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKAAKSA Molecular Formula: C 319 H 495 N 91 O 96 S 7 Molecular Weight: 7365.4225 g/mol PubChem CID: 135331146 CAS Number: 112603-35-7 Synonyms: Insulin-like growth factor 1, des-(1-3)-, Des(1-3) IGF-1, 4-70-insulin-like growth factor 1 IGF-1 DES Research IGF-1 DES Is More Potent Than IGF-1 IGF-1 DES is lacking just three amino acids from its N-terminal end, but that subtle change makes a big difference
10.3390/toxics13070594 14 EngstrmA.WintzellV.MelbyeM.SvanstrmH.EliassonB.GudbjrnsdottirS.et al (2024)
Glutathione (GSH), one of the main body antioxidants, could prevent this phenomenon, but its concentration decreases during aging. Luckily, there are now ways to get your glutathione benefits through medical intervention
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