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cAMP directly activates protein kinase A (PKA) and cAMP-regulated guanine nucleotide exchange factor 2 (Epac2), that act synergistically to generate downstream signals resulting in increased insulin secretion (8)
These medicines have well-characterised safety profiles and are prescribed within a structured clinical pathway that includes monitoring and follow-up
Provider-guided progression Dose changes are clinical decisions based on tolerance and response
E., Welting, O., Wouters, M
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