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After 180 days of exposure, the lowest observable effective concentrations (LOECs) at which citalopram significantly reduced the mean spawning of adult fish were 10 and 1 g/L, respectively, whereas the fertilization rate was not significantly altered

Nevertheless, only recently have studies begun to address NRF2 function in other contexts such as aging and lifespan regulation

10.1016/j.abb.2015.11.023 27 IxJ

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Side effects [edit] The literature data on the acute toxicity profile of hydroxocobalamin show it is generally regarded as safe with local and systemic exposure