This mechanism has positioned AHK-Cu as a compound of interest for researchers studying skin matrix integrity, structural protein regulation, and age-related changes in connective tissue biology
Tested for high purity standards, it is intended strictly for laboratory and research use
The copper chelation capacity of AHK-Cu distinguishes it from unchelated peptide analogs, enabling research into coppers role as a cofactor in angiogenic and wound-response signaling
PMCID: PMC2749291
While there are several types of these receptors, like VEGFR-1, VEGFR-2, and VEGFR-3, it appears that the primary mediator of angiogenic response is most likely VEGFR-2
[1] According to the researchers TGF-beta1 induction of angiogenesis requires a rapid and transient apoptotic effect mediated by VEGF/VEGFR2. AHK-Cu, by enhancing levels of the Vascular Endothelial Growth Factor, may possibly activate fibroblasts and endothelial cells