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The body cannot produce Vitamin B12 independently
And yes, this was done in rats, not humans
To our knowledge, only one study has been conducted among PD patients linking Vit B12 role, the methylation status and the neurodegenerative markers of PD including SN (Obeid et al
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doi:10.1152/ajplegacy.1975.229.2.409
The two compounds in this category target complementary pathways of mitochondrial health: the NAD + activates sirtuins (SIRT1-7) and PARP-1 to restore energy metabolism and DNA repair, while the glutathione neutralizes reactive oxygen species generated by the mitochondrial respiratory chain
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