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DMF induces the expression of L-2-hydroxyglutarate dehydrogenase (L2HGDH) to downregulate L-2-hydroxyglutarate (L2HG) and increase global and locus-specific DNA hydroxymethylation levels
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Weight loss drugs have an important role to play, but they are not a silver bullet, said Katherine Jenner, the executive director of the Obesity Health Alliance, a coalition of more than 50 health, medical and childrens organisations in the UK
Research suggests they may enhance skin pigmentation
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