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Physiology (Bethesda)
Mutations in the leptin gene leading to congenital leptin deficiency are most often seen in offspring of consanguineous marriages
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Ilouz R, Kaidanovich O, Gurwitz D, Eldar-Finkelman H
Its main modes of action are suppressing glucose production in the liver, mostly through inhibition of gluconeogenesis, and opposing the activity of the hormone glucagon (Kishore 2014
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