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Acknowledgements These studies were supported by grants from the Swedish Research Council (4792), the Free Masons in Stockholm for Children's Welfare, the Memory Foundation of Golje, the HRH Crown Princess Lovisa Foundation, the ke Wiberg Foundation, the Ronald McDonald Foundation, the Linna and Josef Carlsson Foundation, the Lennanders Foundation, the Swedish Society of Medicine, and the Samariten Foundation, which are gratefully acknowledged

Introduction Although nitric oxide (NO) has been posited as a deleterious molecule from a physiological perspective (Naseem, 2005), respiratory diseases (Soodaeva et al., 2020), neurodegenerative diseases (Snyder, 1992), and metabolic dysfunction ( In the context of exercise, nitrate supplementation has gained interest as an ergogenic aid to enhance endurance performance ( Therefore, the purpose of this review is to present the general knowledge of the underlying physiological mechanisms affected by NO and the subsequent effect of nitrate supplementation in exercise

3 Brain Sciences (PubMed)Sun et al