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Semaglutide was associated with significantly greater reductions in body weight, waist circumference, and hip circumference at both 3 and 6 months
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If directed, take the capsule with food to enhance absorption and prevent stomach upset
Delayed gastric emptying can create feelings of fullness or discomfort, further reducing food and fluid intake
Semaglutide (Wegovy) dose ladder: 0.25mg 0.5mg 1mg 1.7mg 2.4mg (maintenance) escalating every 4 weeks Tirzepatide (Zepbound/Mounjaro) dose ladder: 2.5mg 5mg 7.5mg 10mg 12.5mg 15mg (maintenance) escalating every 4 weeks Tirzepatides longer escalation path means it may take patients slightly longer to reach full therapeutic effect, but this also allows more time for GI side effects to settle