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The SUSTAIN-6 trial, which tracked over 3,000 patients using semaglutide for diabetes management, reported depression or depressed mood in less than 2% of participants taking the medication versus similar rates in the placebo group
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By addressing not only the metabolic challenges but also the cognitive and cardiovascular aspects of bipolar disorder, GLP-1 agonists demonstrate a holistic approach to treatment that may significantly improve patient outcomes
Gastroenterology Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R (2024) Association of semaglutide with risk of suicidal ideation in a real-world cohort
doi: 10.1016/j.ejphar.2009.12.023 175 McCleanPLParthsarathyVFaivreEHolscherC