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(medschool.cuanschutz.edu) The study also stated that GLP-1 associated weight loss may increase the risk of fracture due to associated muscle loss and trabecular bone loss from the decreased mechanical load on bone
On the cardiovascular side, the SUSTAIN-6 trial in 2016 was one of the first to report a significant reduction in major adverse cardiovascular events with semaglutide in adults with type 2 diabetes and high cardiovascular risk (Marso et al., NEJM, 2016)
These are usually more noticeable when treatment starts or when the dose is increased
Focus on a comprehensive approach
Many people take their supplements haphazardly, which can lead to poor absorption and wasted nutrients
Sahu A, et al
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