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The compound was first characterised in early-1970s aged-liver research by Loren Pickart, who isolated a serum factor that restored synthetic activity in aged-liver tissue cultures and sequenced it as the three-residue Gly-His-Lys fragment

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Farhan, S

Its selectivity is its signature trait unlike older GHRPs (GHRP-6, GHRP-2), it produces GH release with minimal cortisol or prolactin effects, making it a cleaner research tool