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Why it matters: The launch of Indias generic semaglutide signals global GLP-1 pricing and competition, especially as Novos semaglutide also faces patent losses in Canada, China and Brazil
23 As shown in TABLE 2 , recommended nonpharmacologic interventions to reduce GI AEs include dietary modifications such as eating smaller, more frequent meals
In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1
Cell 166 , 209221 (2016)
The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies
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