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Using tirzepatide alongside growth hormone secretagogues like ipamorelin or CJC-1295 may preserve lean mass better during aggressive fat loss

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References 1 FASEB JournalBiological activities of thymosin beta-4 mapped to active peptide sequences, including the fragment marketed as TB-500

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The NICE Guideline NG239 (2024) and the AAFP clinical review both support this approach