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In short: Neanderthals were not modern humans , and what is evolutionarily appropriate for them may not be so for us

In rodent studies, lutein may help reduce oxidative stress, confirmed by a decrease in extracellular signal-regulated kinase (ERK) activation and brain-derived neurotrophic factor (BDNF), along with an increase in glutathione (GSH) and glutathione peroxidase (GPx)

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Aliment Pharmacol Ther 2025

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While some boutique clinics suggest a synergy between these two, the reality is more complex and requires careful clinical consideration