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Consider making a GP appointment if: Your BMI is 30 kg/m or above (or 27.5 kg/m or above if you are of South Asian, Chinese, or other high-risk ethnicity), or your waist circumference exceeds the risk thresholds described above Your BMI is 28 kg/m or above with a weight-related health condition such as type 2 diabetes, hypertension, or dyslipidaemia You have noticed a significant or unexplained increase in abdominal girth You have a family history of type 2 diabetes, cardiovascular disease, or metabolic syndrome You are considering using any weight loss supplement or medication and want to ensure it is safe for you You have tried lifestyle changes without success and wish to explore further options Seek urgent medical attention if you experience: Severe or persistent abdominal pain, particularly if it radiates to the back or is accompanied by fever or vomiting Sudden abdominal distension with breathlessness Unexplained weight loss (without intentional dieting) Persistent abdominal bloating lasting more than three weeks, particularly in women (which should be assessed to exclude ovarian pathology) Rectal bleeding or a change in bowel habit lasting more than three weeks Jaundice, dark urine, or pale stools These symptoms may indicate conditions unrelated to weight that require prompt assessment

Clinical studies show greater weight reduction compared to semaglutide alone

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Seek urgent medical attention (call 999, go to A&E, or contact NHS 111) if: Body odour changes are accompanied by a sweet, fruity breath smell , excessive thirst, frequent urination, fatigue, or confusion these could indicate diabetic ketoacidosis (DKA), a serious complication requiring immediate treatment You experience severe, persistent abdominal pain (especially radiating to the back) with or without vomiting, which could indicate pancreatitis You develop severe pain in the upper right abdomen , fever, or yellowing of the skin/eyes, which might suggest gallbladder problems Contact your GP promptly if: You notice unusual or foul-smelling discharge from injection sites, which might suggest infection Odour changes coincide with persistent gastrointestinal symptoms such as vomiting or diarrhoea that could lead to dehydration You develop unexplained fever, night sweats , or unintentional weight loss beyond what's expected with treatment You experience sudden changes in vision , particularly if you have pre-existing diabetic retinopathy The odour is accompanied by skin changes , rashes, or other new symptoms Arrange a routine appointment to discuss: Persistent body odour concerns that affect your quality of life or confidence, even if not medically serious Any side effects that make you consider stopping Ozempic, as your doctor may adjust your dose or suggest alternative management strategies Questions about whether your symptoms are normal or require investigation Your healthcare team can perform a comprehensive assessment including review of your diabetes control (HbA1c levels), kidney and liver function tests, and evaluation for other potential causes of odour changes such as thyroid disorders, infections, or medication interactions