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Furthermore, triple therapy increased insulin sensitivity three-fold and beta-cell function 30-fold while sequential treatment did not improve insulin sensitivity and led to a more modest 34% increase in beta-cell function

Comparative efficacy of THR- agonists, FGF-21 analogues, GLP-1R agonists, GLP-1-based polyagonists, and Pan-PPAR agonists for MASLD: a systematic review and network meta-analysis

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