Antioxid Redox Signal (2012) 16:70543
The 9mg dose produced 26.4% weight loss, or roughly 64 pounds
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This contraindication exists because MTC arises from the same C-cells that showed tumor formation in rodent studies, and individuals with MTC history may have underlying genetic susceptibility that could theoretically interact with GLP-1 receptor stimulation
Not everyone, however, was convinced that glucagon needed to be blocked to encourage weight loss
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