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Table 2: Microbial metabolites: their synthesis, mechanisms of action, and effects on health and disease Figure 1: Molecular mechanisms of action of indole and its metabolites on host physiology and disease 1 2 "Trace amine-associated receptors: ligands, neural circuits, and behaviors"

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Hemoglobin A1c

The most clinically documented interaction is with cyclosporine, where berberine can significantly increase blood levels, potentially requiring dose adjustments and therapeutic drug monitoring

Nano-formulated curcumin (Lipodisq) modulates the local inflammatory response, reduces glial scar and preserves the white matter after spinal cord injury in rats