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Hillman D, Mitchell S, Streatfeild J, Burns C, Bruck D, Pezzullo L

In clinical studies, once-weekly administration of the GLP-1 agonist semaglutide in knee OA patients with obesity reduced patient-reported pain scores (WOMAC) over 68 weeks compared with placebo

Inject at Bedtime Nighttime dosing aligns with the bodys natural growth hormone rhythm and may reduce awareness of early systemic symptoms like flushing or nausea

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