Both peptides demonstrated strong ACE-inhibitory activity, with IC values of 0.92 mol/L for TTP and 3.4 mol/L for gAgAP
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Harmonic restraints of 50.0 kcal mol 1 2 were applied to the solutes, including the crystallographic ions, to allow solvent relaxation while preserving the maximum fidelity to the docking pose, and the Andersen temperature coupling scheme 81,82 was used to control and equalize the temperature
Each batch undergoes meticulous quality control verification prior to release, including HPLC purity analysis, mass spectrometry confirmation, and endotoxin testing where applicable