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In people with type 2 diabetes, retatrutide reduced HbA1c by 2.2% after 36 weeks
Patients who are currently using medications containing semaglutide should approach this information aware and engaged
The trial was sponsored by Novo Nordisk, the company that developed semaglutide
The Prescription Toolbox for Obesity Liraglutide: Mechanism, Dosing, Typical Results Liraglutide vs Semaglutide (Wegovy/Ozempic) Liraglutide vs Tirzepatide (Zepbound/Mounjaro) Liraglutide vs Oral & Combination Pills (Qsymia, Contrave, Orlistat) Which Medication Should You Choose
What is known is that in one study, after 68 weeks, those who stopped this medication regained two-thirds of their prior weight loss
However, current evidence is still inconclusive to demonstrate a direct negative effect of GLP-1 RAs on LBM loss, largely due to heterogeneity in study designs and the limited number of trials specifically evaluating this endpoint [77]
