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Platelet derived growth factor (PDGF) also plays a role in this process as it is mitogenic and chemotactic for connective tissue cells and stimulates collagenase production and synthesis of ECM components, such as fibronectin and hyaluronic acid

Mol Aspects Med 30, 4259, 10.1016/j.mam.2008.05.005 (2009)

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It works best when combined with adequate hydration, nutrition, and reducing ongoing toxin exposure

However, they need to make sure the supplement provides acceptable amounts of vitamin B12 made from high-quality ingredients

Dec 2023;5(12):100730