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All housing, handling, and experimentation that involved the rats were conducted following the procedures set in place by the National Institutes of Health guide for the care and usage of laboratory animals [2]

To compensate for this sudden loss of blood pressure, the autonomic nervous system triggers severe tachycardia (a rapid heart rate), manifesting as Postural Orthostatic Tachycardia Syndrome (POTS) and other forms of dysautonomia