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When to seek medical attention: Contact your GP promptly if you experience recurrent episodes of right upper abdominal pain Seek urgent medical assessment (A&E or call 999) if you develop severe persistent pain, high fever, jaundice, or signs of sepsis If you develop severe, persistent abdominal pain that radiates to your back, especially with vomiting, seek urgent medical care as this could indicate pancreatitis

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This approach has become the standard with GLP-1 and GIP receptor agonists because rapid introduction at high doses often leads to nausea, vomiting, or diarrhea severe enough for patients to discontinue treatment

Ask a clinician or pharmacist before using acetaminophen, ibuprofen, naproxen, or aspirin if you have liver or kidney disease, ulcers, bleeding risks, or take anticoagulants

Available at: (accessed May 2019) [73] Frey N, Bodmer M, Bircher A et al

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