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However, a large phase 3 trial of oral semaglutide found it wasnt effective at slowing clinical disease progression
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Semaglutide stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it only triggers insulin release when blood sugar levels are elevated, thereby reducing the risk of hypoglycaemia when used alone
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We can deduce from the figure above that 32.2% of the semaglutide group lost less than 5% of their body weight, while 22.9% lost more than 15% of their body weight a decent amount of variation
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