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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement
Mycyk, MD Publishers Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
If youve been considering weight loss medications, youve probably come across terms like liraglutide, semaglutide , and GLP-1
30 Notably, 18% of patients had a prior LVEF 40, and 42% had undocumented LVEF
Dose increases should only happen when nausea is mild or has mostly resolved
Our findings highlight the potential of GLP1 RAs to significantly influence HFpEF progression and improve key clinical outcomes reinforcing their role as a promising therapeutic strategy
