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Mechanism of Action Comparison# Bioglutide (NA-931)# Bioglutide is an oral small molecule that simultaneously activates four metabolic hormone receptors: GLP-1 (appetite suppression, glucose homeostasis), GIP (incretin potentiation), glucagon (energy expenditure, hepatic fat reduction), and IGF-1 (muscle preservation, anabolic signaling)

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SURMOUNT SURMOUNT 15% 20% 25% MOUNJARO 4 BMI 30 BMI 27 MTC MEN 2 Tirzepatide (Mounjaro/Tirzepatide) LINE FB 48 SURMOUNT 12-24 15-20% 6 1 2.5mg FDA EMA (TFDA) NT 15,000

Circulation 150 , 12161218 (2024)

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