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Significantly higher urinary opioid peptide concentrations were detected in Rett Syndrome compared to both autism and control groups

5 mg subcutaneously once daily , morning, 8 12 weeks on and 4 weeks off

Alleviated some pain, but relief was only temporary

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Four participants were enrolled in the 1 10 6 cells/one tooth group and randomly assigned to the experimental group (three cases) or the saline injection group (one case), while for the remaining four dose groups, eight participants were enrolled in each group and randomly assigned to the experimental group (six cases) or the saline injection group (two cases)

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