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Trappe SW et al

It helps reduce appetite and can lead to significant weight loss over time

Thyroid C-cell tumors have been observed in rodent studies, though human cases remain theoretical

doi: 10.1007/s13181-018-0653-9 [PubMed] 29605069 Bunchorntavakul C, Reddy KR

Epac activates the MAPK pathway, thereby promoting the activity of cyclin-dependent kinase 2 (CDK2) and CDK4, which in turn facilitate -cell differentiation and proliferation [35, 36] (Fig

10.1001/jama.2021.1831 31

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