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Chemical composition, synthesis, and structure-elucidation Molecular composition Esculetin (6,7-dihydroxycoumarin) is a naturally occurring hydroxycoumarin with an aromatic lactone structure
Animal studies show the peptide can recruit the azygos vein system during caval vein occlusion, parasagittal veins for compromised brain circulation, and pancreaticoduodenal arteries when mesenteric vessels become blocked
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Second, the 39-residue chain length means lower overall synthesis yields compared to shorter peptides, because each coupling step has a less-than-perfect success rate that compounds across the chain
