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While the DHFR-TS1 and 2 are enzymatically functional but also redundant, DHFR-TS3 is a nonenzymatic isoform known to inhibit the activities of its counterparts (Gorelova et al
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d , A model of Ex4-D-Ala fitted (using ISOLDE) to the receptor-focused density map of Ex4-D-Ala conf
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