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These events occurred after several weeks of G
The low GSH concentration necessary for CVA21 displacement may also limit a co-elution of potentially bound host cell GST enzymes present in cell culture harvests, which may require as high as 10 mM GSH for elution (Figure 4A) and elution NaCl gradient (Supplementary Figure S6C) studies where CVA21 particles eluted at lower ionic strengths with increasing pH
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Nat Commun 17 , 181 (2026)
Aminoisobutyric acid (Aib) at position 1 confers N-terminal stability against aminopeptidase degradation
Hypoxia-inducible factor-1: a novel therapeutic target for the management of cancer, drug resistance, and cancer-related pain
