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The 3 mg dose is for initiation only (first 30 days) and not intended for glycemic control
doi: 10.1111/imr.12603 107 KolliniatiOIeronymakiEVergadiETsatsanisC
Animal experiments and studies of human subjects have shown that IOP-independent factors include oxidative stress, glutamate excitotoxicity, and impaired retinal blood flow 6,7,8
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Its practical advantage over earlier quinolinium analogues is permeability
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