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Here, we report that ALC reduced SREBP2 and HMGCR expression in mouse livers and human hepatoma cells and increased the expression of cholesterol metabolism-related genes, such as Ldlr , in the livers of ALC-fed mice

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Discovery and Research History (Pickart, 1973Present) Pickart's foundational observation was that plasma from young donors caused liver cells from older donors to behave more like young tissue