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However, what many people describe as a "color change" might actually be a change in the clarity of the eye

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This may indicate inadequate nutrition, an underlying medical condition, or a need for treatment modification

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Cysteine residues may also react with heavy metal ions (Zn 2+ , Cd 2+ , Pb 2+ , Hg 2+ , Ag + ) because of the high affinity between the soft sulfide and the soft metal (see hard and soft acids and bases)