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Cells were harvested and resuspended in lysis buffer, lysed by sonication, and clarified by centrifugation

Following this, novel GLP-1R/GIPR/GcgR tri-agonists, achieved through antibody-based constructs, have been developed

This potent combination works at a cellular level to reduce melanin production, fight oxidative stress, and gradually lighten pigmented areas

It helps maintain cellular homeostasis by modulating oxidative stress, assisting in protein repair, supporting mitochondrial function, sustaining DNA integrity, and influencing inflammatory pathways

Oxidative stress is also reduced by the structural maintenance of mitochondria exerted by GLP-1 and by its upregulation of anti-oxidative molecules

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