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Learning to avoid them is crucial
Last reviewed: May 22, 2026 Last updated: May 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
55,58,59 Therefore, NNMT and CYP2E1 divert NAM from recycling to NAD + , restraining NAM accumulation and inhibition of NAD + -dependent signaling
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Nutrients that support liver detoxification and healthy estrogen metabolism, such as DIM, along with botanicals like vitex that support hormonal signaling, can help reduce estrogen recirculation and promote hormonal balance
Tools like the SeekPeptides peptide calculator can help researchers plan their protocols around these nutritional requirements
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