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Concretely, lactylation of NEDD4, a negative regulator of Caspase-11, impedes Caspase-11 ubiquitination by decreasing its interaction with Caspase-11, thereby triggering pyroptosis in macrophages and exacerbating acetaminophen-induced liver injury (AILI)

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Bioavailability refers to how much of a nutrient actually enters your bloodstream and reaches your cells

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