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10.1111/bph.13616 31 CortiA.DominiciS.PiaggiS.BelcastroE.ChiuM.TaurinoG.et al (2019)

Mol Cell Biol , 34: 34213434, 2014

While this creates a daytime pulse and may boost morning energy and alertness, it doesn't leverage the robust nocturnal pulse and sleep-associated benefits of bedtime dosing