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Mean heart rate increased slightly by 0.94 beats per minute with combination therapy versus decreases in other groups

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Funding This research was funded by the National Key Research and Development Programs of China, grant number 2022YFC2603801, the Maternal and Child Health Project of Jiangsu Province (F201717), the Doctor Project of Affiliated Hospital of Jiangsu University (jdfyrc2019003), and Clinical and Virology Study of 2019-ncov Infection in Patients with Moderate to Severe Psoriasis (Jdfyxgzx005). Publishers note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Timeline of changes after stopping GHK-Cu The post-discontinuation timeline follows predictable patterns based on skin biology and collagen turnover kinetics, though individual variation creates significant range in experiences depending on treatment duration, application frequency, concentration used, baseline skin condition, age, lifestyle factors, and genetic collagen production capacity

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