Semaglutide, the active ingredient in Wegovy, mimics the hormone GLP-1, which regulates appetite, blood sugar, and how quickly food moves through your digestive system
(PMC) Why people stack it with GH-axis peptides The stack theory is: AOD mobilizes fat while GH secretagogues improve body composition and recovery. What the science supports (and what it doesnt) Supported with more confidence: AOD-9604s mechanistic target (fat metabolism signaling) is plausible, and it has been studied in obesity contexts
Tirzepatide (Mounjaro) is a dual GIP/GLP-1 receptor agonist approved by the FDA for type 2 diabetes, offering substantial HbA1c reductions of 1.9% to 2.6%
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Demonstrates collagen stimulation and skin improvement at 1-2mg daily doses n.d
Both figures come from peer-reviewed NEJM trials of FDA-approved active ingredients in controlled settings - not from compounded formulations or any specific platform