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Structure and Classification Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a pentapeptide growth hormone secretagogue developed by Novo Nordisk in the 1990s

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Most peptides are self-injected subcutaneously (under the skin) using a small insulin-type needle

These drugs, like semaglutide and tirzepatide, have been rigorously tested over years of clinical human trials and have been FDA approved to treat obesity

In this brief report, the authors describe multiple cases of patients with psoriasis, hidradenitis suppurativa, acanthosis nigricans, and Hailey-Hailey disease for which patients experienced improvement subsequent to treatment with GLP-1 therapy