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Early clinical studies suggest that Retatrutide provides greater efficacy in weight management and glucose regulation compared to single or dual receptor agonists such as semaglutide or tirzepatide, due to its synergistic triple-receptor mechanism

We used a human BBB co-culture model improved by cARLA treatment, as described in our paper [40], for the impedance, cellular uptake and permeability experiments

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FAS: n = 20 in NAC- and 19 in placebo-group, due to poor NAC-compliance) (Fig