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GHK-Cu, or copper tripeptide-1, occurs naturally in the body, from plasma to saliva, but levels decline with age

Topical and low-dose exposures seem safe in small studies

CJC-1295 (a modified GHRH analogue) stimulates pulsatile release of growth hormone, while Ipamorelin (a selective ghrelin receptor agonist) enhances this effect without significantly impacting cortisol, prolactin, or ACTH levels

In a 2003 in vitro experiment by Khavinson and colleagues, addition of micromolar concentrations of the peptide to cultured human somatic fibroblasts produced a measurable increase in telomerase reverse transcriptase activity and a corresponding extension of telomere length across 1020 passages, with cell cultures continuing to divide beyond the Hayflick limit observed in untreated controls

Andersen NB, et al

Oral supplements must pass through your digestive system, where much of their potency can be lost